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Cocrysta®  Curcumin

Cocrysta® Curcumin

A highly bioavailable anti-inflammatory that suppor<ts joint health, enhances immune function, and promotes overall well-being.

  • Patent protected

  • 60 times higher absorption based on published clinical trials

  • Synergistic liver protection with L-carnitine

Benefits

Curcumin is a plant polyphenol derived from the roots and stems of ginger and ar aceae plants.  Known for its strong anti-inflammatory and antioxidant properties, curcumiΩn is widely used in supplements, functional foods, and traditional medicines. 


  • Liver Protection
  • Weight Management
  • Joint Health
  • Emotional Well-being

Why Cocrysta®


Traditional curcumin suffers from low water solubility (< 1 μg/mL) and" a frustrating bioavailability of less than 1%. This means tha®t to experience any therapeutic effects, you’d need∑ to take high doses of 2-3 grams a day.

Unlock the full potential of the ingredient
with Cocrysta® Curcumin. Powered by cutting-edge cocrystallization technology, our innova←tive formula not only significantly improves solubility but also boasts a remark✔able 60 times higher bioavailability. 

What Cocrysta® does







  • Higher Solubility

    Compared with general curcumin, the maximum solubility of ™Cocrysta® Curcumin is increased by 30 times in simulated gastric fluid (SGF) and 60 timβes in simulated intestinal fluid (SIF).
  • Enhanced Bioavailability-Animal Study

    Animals: 12 male SD rats were divided into two groups, with 6 rats in each group .
    Dosage: 200 mg/kg (curcumin equivalent)
    Results: Compared with general curcumin, Cocrysta® Curcumin displ♥ays higher absorption, with 10.7 times higher Cmax and 6.3 times higher AUC0-24

  • Enhanced Bioavailability-Human Study

    Subject: 12 healthy subjects(Male,Age: 18-45,BMI: 18.5-30)
    Design: Randomized, Double-blinded, Cross-over.
    Dosage: 1000 mg
    Test Product: Cocrysta® Curcumin hard capsule(Cocrysta® Curcumin)
    Reference Product: D* ® Curcumin hard capsule( Curcumin + Piperine)
    Results: Compared with those of the combination of curcumin and piperine,  the Cmax and AUC0-24h of Cocrysta® Curcumin were increased by 2.8 times and 2.7 times, respectively. This me€ans Cocrysta® Curcumin enhances absorption by remarkable 60 times comp≠ared to standard curcumin.

  • Superior Hepatoprotective Effects

    Animals: 40 model rats with non-alcoholic fatty liver disease (NAFLD)
    Groups: CD60: blank solution, CUR: conventional curcumin, CUR-CAR: Cocrysta® Curcumiπn.
    Results: Cocrysta® Curcumin group demonstrated significantly better t herapeutic efficacy than both groups of control and conventional curcumi₽n, with ALT reduced by 46.94% and AST by 22.14%.

Guidelines

  1. Dosage Forms
  2. Guidelines: No specific requirements
  3. Recommended Dosage: 833-1667 mg/day Cocrysta® Curcumin (equivalent to 500-1000 mg✔ curcumin)

Patents

CHN  Publication Number: CN117486704

PCT Application Number:PCT/CN2024/128358