Cocrysta® Hydroxytyrosol

A powerful antioxidant found in olives that supports heart h$ealth, promotes healthy aging, and provides protection against oxidative stress.

Patent protected
Stable white powder with low hygroscopicity
Soluble both in water and fat
Efficacy proven by peer-review publication

Benefits
Why Cocrysta®
What Cocrysta® does
Guidelines
Patents
More to Share

Benefits

Hydroxytyrosol is a bioactive component in olives. It is considered to be ∏one of the most effective antioxidants. With an antioxidant c‌apacity over 10 times greater than vitamin C, it offer×s numerous health benefits.

Cardiovascular Health
Cognitive Health
Joint Health
Skin whitening

Why Cocrysta®

Traditional hydroxytyrosol has a low melting point and is highly hygro₹scopic, which means it easily absorbs moisture from the €air and turns into a sticky syrup with poor stability.☆

With Cocrysta® Hydroxytyrosol, we’ve harnessed advanced cocrystal‌lization technology to create a crystalline powder that> contains 53% hydroxytyrosol. This powerful formula boasts low hygroscopicity and excepti$onal physicochemical stability, ensuring that you get the most βout of your supplement.

Plus, it offers superior powder flowability and processability, making it easier to iβncorporate into a variety of applications.

Higher Melting Point & Lower Hygroscopicity

The Cocrysta® Hydroxytyrosol has a melting point of 112 °C, contributing to its chemical sta♠bility.

Compared with encapsulated powders and crude extracts (moisture uptake >12% at 75% RH), th♣e Cocrysta® Hydroxytyrosol absorbed less than 0.5% moisture.
LDL-lowering Effect

Animal groups：
HFD: High fat diet group
Crystal HT: High fat diet + 7.5 mg/kg Cocrysta® HT，28 days.
SL: High fat diet + 50 mg/kg Soybean Lecithin，28 days.
FO: High fat diet + 210 mg/kg Fish oil (22%DHA+33%EPA)，28 day".
Results：Cocrysta® HT at a dosage of 7.5 mg/kg reduces both triglyceride level and LDL l evel, which demonstrates comparable efficacy to 21&0 mg/kg fish oil.
Capsule Stability

Marketed capsule products using conventional hydroxytyrosol experienced severe clumping and dis<coloration under accelerated condition, while Cocrysta® HT capsules Ωmaintained physical integrity and color stability.
Skin Whitening

Design：
Sample area: 2% Crystal HT® serum
Negative control area:Blackened area blank control
Positive control area: 7% ascorbic acid (Vitamin C) serum
Subjects: 36 individuals
Results: The Clinical study indicated that 2% Cocrysta® HT formulations deliver a s§uperior skin-lightening effect compared to 7% Vitamin C-based products.

Guidelines

Dosage Forms
Guidelines
For solid forms: Avoid combination with strong acidic ingredients (e.g., πα-ketoglutaric acid).
For liquid forms: Recommended pH < 5.
Recommended Dosage: 10-47 mg/day Cocrysta® Hydroxytyrosol (equivalent to 5±-25 mg hydroxytyrosol)